Description

6'-Amino-3'-butyl-2-oxo-1,2-dihydro-2'H-spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile is a high-purity, complex heterocyclic compound featuring a unique spirocyclic architecture that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a sophisticated intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on creating new active ingredients with specific biological profiles. The precise structure offers a versatile scaffold for further functionalization, enabling the exploration of new chemical spaces for drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Scaffold: Used as a privileged core structure for constructing compound libraries in high-throughput screening (HTS) campaigns to identify novel bioactive hits.
• Agrochemical Research: Acts as an intermediate in the synthesis of potential new pesticides or herbicides, leveraging its complex heterocyclic system.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes to study enzyme function or protein-protein interactions within biological systems.
• Organic Electronic Materials Research: Investigated as a potential component in the development of novel organic semiconductors or light-emitting materials due to its conjugated system.
• Academic Research: Employed in universities and research institutes for methodological studies in synthetic organic chemistry, particularly in spirocycle formation and heterocyclic chemistry.

Basic Information

Product Name	6'-Amino-3'-butyl-2-oxo-1,2-dihydro-2'H-spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile
CAS No.	674807-32-0
Molecular Formula	C19H19N5O2
Molecular Weight	349.39 g/mol
Synonyms	6'-Amino-3'-butyl-2-oxo-1,2-dihydrospiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile; 2'H-Spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile, 6'-amino-3'-butyl-1,2-dihydro-2-oxo-; 6-Amino-3-butyl-2-oxo-1,2-dihydro-2H-spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5-carbonitrile; Spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile, 6'-amino-3'-butyl-1,2-dihydro-2-oxo-; 674807-32-0; AKOS025310643; BCP34033; ZINC000257830587.
EINECS	Contact for details

Quality Control

Our 6'-Amino-3'-butyl-2-oxo-1,2-dihydro-2'H-spiro[indole-3,4'-pyrano[2,3-c]pyrazole]-5'-carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/LC-MS for structural confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request. We support custom synthesis with purity levels tailored to your project requirements, from standard research grade to GMP-grade intermediates for advanced development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.