Description

4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Olhydrochloride is a high-purity, versatile organic building block with a unique cyclic ether and amino alcohol hydrochloride structure. This compound is valued for its dual functionality, serving as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce amino and hydroxyl functional groups into polymer backbones, enhancing properties like adhesion, cross-linking, and biocompatibility.
• Peptidomimetics Research: The aminomethyl and hydroxyl groups make it a valuable scaffold in designing and constructing peptidomimetic compounds for medicinal chemistry.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.

Basic Information

Item	Details
Product Name	4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Olhydrochloride
CAS No.	666261-01-4
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	4-(Aminomethyl)tetrahydro-2H-pyran-4-ol hydrochloride; 4-(Aminomethyl)tetrahydropyran-4-ol HCl; 4-(Hydroxymethyl)tetrahydropyran-4-amine hydrochloride; 4-Aminomethyl-4-hydroxytetrahydropyran hydrochloride; 4-Piperidinemethanol, 4-amino-, hydrochloride; (4-Hydroxytetrahydropyran-4-yl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Olhydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.