Description

Cyclohexanecarboxylic Acid, 2-Hydroxy-1-Methyl-, (1R,2S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its rigid cyclohexane backbone and functional handles, which are critical for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and anti-infectives.
• Asymmetric Synthesis: Serves as a precursor or ligand in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Fine Chemical Production: Used in the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and process development in pilot plants.
• Agrochemical Synthesis: Potential intermediate for creating chiral active ingredients in advanced crop protection products.
• Material Science: Building block for chiral polymers or advanced organic materials with specific optical properties.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-Hydroxy-1-Methyl-, (1R,2S)-Rel- (9Ci)
CAS No.	666260-23-7
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(1R,2S)-rel-2-Hydroxy-1-methylcyclohexanecarboxylic Acid; rel-(1R,2S)-2-Hydroxy-1-methylcyclohexanecarboxylic Acid; 2-Hydroxy-1-methylcyclohexanecarboxylic Acid (relative (1R,2S) configuration); (1R,2S)-2-Hydroxy-1-methyl-1-cyclohexanecarboxylic Acid (relative); Cyclohexanecarboxylic acid, 2-hydroxy-1-methyl-, (1R,2S)-rel-; Chiral Cyclohexane Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 2-Hydroxy-1-Methyl-, (1R,2S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.