Description

6-Nitro-Chroman-4-Ylamine Hydrochloride is a high-purity organic chemical intermediate of significant importance in advanced synthetic chemistry. This compound serves as a critical building block for the development of novel pharmaceutical agents and complex organic molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) or cardiovascular targets.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct complex chroman-based heterocyclic frameworks.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical spaces and reaction methodologies.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Fine Chemical Production: Used in the manufacture of specialty and performance chemicals requiring specific chroman-amine architectures.

Basic Information

Product Name	6-Nitro-Chroman-4-Ylamine Hydrochloride
CAS No.	662228-22-0
Molecular Formula	C9H11N2O3·HCl
Molecular Weight	246.66 g/mol
Synonyms	4-Amino-6-nitrochroman hydrochloride; 6-Nitro-4-chromanamine hydrochloride; 4-Amino-6-nitro-3,4-dihydro-2H-1-benzopyran hydrochloride; 2H-1-Benzopyran-4-amine, 6-nitro-, hydrochloride; 6-Nitrochroman-4-amine HCl; 4-Amino-6-nitrochroman HCl salt; 6-Nitro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Nitro-Chroman-4-Ylamine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring it meets the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.