Description

4H-Pyran-4-One,2-(4-Ethylphenyl)-2,3-Dihydro-,(-)-(9Ci) is a chiral, substituted dihydropyranone compound with the CAS registry number 658704-85-9. This specific stereoisomer is of significant interest in advanced organic synthesis, particularly for constructing complex molecular architectures with precise stereochemical control. It serves as a critical chiral building block or synthetic intermediate for researchers and manufacturers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring specific enantiomeric purity.
• Asymmetric Synthesis: Utilized as a precursor or scaffold in catalytic asymmetric reactions to introduce the dihydropyranone moiety into target molecules.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, agrochemicals, and advanced materials where its specific stereochemistry imparts desired properties.
• Academic & R&D: Used in university and industrial research laboratories for methodological studies in organic chemistry and the exploration of new synthetic pathways.
• Ligand and Catalyst Development: Potential use as a precursor for chiral ligands or organocatalysts used in enantioselective transformations.

Basic Information

Product Name	4H-Pyran-4-One,2-(4-Ethylphenyl)-2,3-Dihydro-,(-)-(9Ci)
CAS No.	658704-85-9
Molecular Formula	C13H14O2
Molecular Weight	202.25 g/mol
Synonyms	(-)-2-(4-Ethylphenyl)-2,3-dihydro-4H-pyran-4-one; (S)-2-(4-Ethylphenyl)-2,3-dihydro-4H-pyran-4-one; 2-(4-Ethylphenyl)-2,3-dihydro-4H-pyran-4-one, (-)-; 658704-85-9; 4H-Pyran-4-one, 2-(4-ethylphenyl)-2,3-dihydro-, (-)-; 2-(p-Ethylphenyl)-2,3-dihydro-4H-pyran-4-one, (-)-
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing specific parameters such as assay, enantiomeric excess (ee), and impurity profile is provided with every shipment, supporting cGMP-compliant development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.