Description

2H-1-Benzopyran-2-Carboxamide, n-[6-Amino-1,2,3,4-Tetrahydro-3-Methyl-1-(2-Methylphenyl)-2,4-Dioxo-5-Pyrimidinyl]-3,4-Dihydro-6-Hydroxy-2,5,7,8- is a complex heterocyclic compound featuring a benzopyran core fused with a substituted pyrimidinedione moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates with optimized potency and selectivity.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and target validation.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals for advanced applications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	2H-1-Benzopyran-2-Carboxamide, n-[6-Amino-1,2,3,4-Tetrahydro-3-Methyl-1-(2-Methylphenyl)-2,4-Dioxo-5-Pyrimidinyl]-3,4-Dihydro-6-Hydroxy-2,5,7,8-
CAS No.	658061-88-2
Molecular Formula	C22H22N4O5
Molecular Weight	422.44 g/mol
Synonyms	N-[6-Amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylphenyl)-2,4-dioxo-5-pyrimidinyl]-3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxamide; 2H-1-Benzopyran-2-carboxamide, N-[6-amino-1,2,3,4-tetrahydro-3-methyl-1-(2-methylphenyl)-2,4-dioxo-5-pyrimidinyl]-3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-; 658061-88-2; Benzopyran-pyrimidinedione conjugate; Advanced heterocyclic intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for purity, related substances, and residual solvents. Our quality management system supports development under GMP-like conditions for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handle and store under an inert atmosphere if specified for your grade.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.