Description

Bicyclo[4.1.0]Heptane-3-Carboxylic Acid, 4-Amino-4,7,7-Trimethyl- is a high-purity, functionalized bicyclic compound that serves as a sophisticated chiral building block and intermediate in advanced organic synthesis. Its unique rigid, fused-ring structure containing both amino and carboxylic acid functional groups makes it a valuable scaffold for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as in advanced material science for creating specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its bicyclic structure for enhanced biological activity.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Advanced Material Science: A building block for specialty polymers, dendrimers, and liquid crystals requiring rigid, functionalized cores.
• Chemical Research & Development: A versatile intermediate in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.
• Peptidomimetics: Used to incorporate constrained, non-natural amino acid motifs into peptide analogs to improve stability and bioavailability.

Basic Information

Item	Detail
Product Name	Bicyclo[4.1.0]Heptane-3-Carboxylic Acid, 4-Amino-4,7,7-Trimethyl-
CAS No.	654680-86-1
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	4-Amino-4,7,7-trimethylbicyclo[4.1.0]heptane-3-carboxylic acid; 4-Amino-4,7,7-trimethyl-3-norcarenecarboxylic acid; 3-Norcarene-3-carboxylic acid, 4-amino-4,7,7-trimethyl-; Trimethylnorcaranyl amino acid; Amino-trimethylbicycloheptane carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[4.1.0]Heptane-3-Carboxylic Acid, 4-Amino-4,7,7-Trimethyl- is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. Comprehensive analytical testing, including chiral purity assessment, is performed. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.