Description

2H-Pyran-2-One,Tetrahydro-3,4-Dimethyl-6-(1-Methylethyl)-,(3R,4S,6R)-Rel-(9Ci) is a high-purity, stereochemically defined lactone compound of significant interest in advanced organic synthesis. Its specific three-dimensional configuration makes it a valuable chiral building block for the development of complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in projects requiring specific stereochemistry.
• Asymmetric Synthesis: Serves as a versatile chiral building block or auxiliary in catalytic and stoichiometric asymmetric reactions to introduce complex molecular architectures.
• Flavor & Fragrance Precursor: Used in the synthesis of high-value lactone-based aroma chemicals, contributing to complex olfactory profiles.
• Agrochemical Research: Employed as an intermediate in the development of novel, stereospecific pesticides and herbicides.
• Material Science: Investigated as a monomer or precursor for specialized polymers with unique optical or physical properties.
• Academic & Contract Research: A critical reagent for methodological studies in organic chemistry and for custom synthesis projects.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-3,4-Dimethyl-6-(1-Methylethyl)-,(3R,4S,6R)-Rel-(9Ci)
CAS No.	648434-42-8
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(3R,4S,6R)-3,4-Dimethyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; rel-(3R,4S,6R)-3,4-Dimethyl-6-isopropyltetrahydro-2H-pyran-2-one; Tetrahydro-3,4-dimethyl-6-(1-methylethyl)-2H-pyran-2-one, (3R,4S,6R)-rel-; 6-Isopropyl-3,4-dimethyltetrahydro-2H-pyran-2-one; Stereoisomer of whisky lactone precursor; Chiral lactone intermediate.
EINECS	Contact for details

Quality Control

Our production of this chiral lactone adheres to strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Optical Rotation	Specified range provided on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.