Description

1,2,3,4,5-Pentamethyl-6-(Methylthio)Benzene is a highly substituted benzene derivative characterized by its unique sterically hindered and electron-rich thioether functionality. This compound matters as a versatile and valuable advanced intermediate for the synthesis of complex organic molecules, particularly in the development of specialty chemicals and functional materials. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for creating sterically hindered aromatic systems.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where its substituted structure can impart specific biological activity.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing specialized ligands in organometallic chemistry and catalysis due to the methylthio group's coordinating potential.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport molecules or components for organic light-emitting diodes (OLEDs).
• Chemical Reference Standard: Used as a high-purity analytical standard in chromatography for method development and quality control in related chemical processes.
• Organic Synthesis Building Block: Provides a multifunctional, pre-methylated aromatic core for further functionalization in complex multi-step synthetic routes.

Basic Information

Product Name	1,2,3,4,5-Pentamethyl-6-(Methylthio)Benzene
CAS No.	646498-12-6
Molecular Formula	C12H18S
Molecular Weight	194.34 g/mol
Synonyms	Hexamethylbenzenethiol (misnomer); 6-(Methylthio)pentamethylbenzene; 1,2,3,4,5-Pentamethyl-6-(methylsulfanyl)benzene; Methylthiopentamethylbenzene; Pentamethyl(methylthio)benzene; 1-Methylthio-2,3,4,5,6-pentamethylbenzene; NSC 406915
EINECS	Contact for details

Quality Control

Our 1,2,3,4,5-Pentamethyl-6-(Methylthio)Benzene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to support cGMP compliance for use in regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.