Description

1,2-Cyclohexanediamine,4-Methyl-,(1R,2R)-Rel-(9Ci) is a high-purity, chiral diamine building block of significant importance in asymmetric synthesis. Its rigid cyclohexane backbone and stereodefined configuration make it a valuable ligand and precursor for creating enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing chiral catalysts, resolving agents, and advanced pharmaceutical intermediates.

Application

• Chiral Ligand Synthesis: A key precursor for the preparation of salen-type and other chelating ligands used in asymmetric catalysis.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Development: Used in the research and production of metal-complex catalysts for enantioselective hydrogenation, epoxidation, and other transformations.
• Chiral Resolution Agent: Employed to separate racemic mixtures of acids or other compounds due to its defined stereochemistry.
• Advanced Material Research: Investigated for the synthesis of chiral polymers, metal-organic frameworks (MOFs), and other functional materials.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	1,2-Cyclohexanediamine,4-Methyl-,(1R,2R)-Rel-(9Ci)
CAS No.	636563-62-7
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(1R,2R)-4-Methylcyclohexane-1,2-diamine; (1R,2R)-1,2-Diamino-4-methylcyclohexane; (1R,2R)-4-Methyl-1,2-cyclohexanediamine; (1R,2R)-4-Methyl-1,2-diaminocyclohexane; rel-(1R,2R)-4-Methylcyclohexane-1,2-diamine; (1R,2R)-TMCDA; (1R,2R)-4-Methyl-CHDA
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanediamine,4-Methyl-,(1R,2R)-Rel-(9Ci) is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment aligns with the standards required for GMP and ISO-guided manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product quality. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.