Description

5-Chlorothiophene-2-Boronic Acid Pinacol Ester is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex, functionalized heterocyclic systems. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex thiophene scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific chlorinated heterocyclic structures.
• Material Science: Serves as a building block for creating organic electronic materials, such as semiconductors for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new C-C bond formation methodologies and creating compound libraries.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and coordination chemistry.

Basic Information

Product Name	5-Chlorothiophene-2-Boronic Acid Pinacol Ester
CAS No.	635305-24-7
Molecular Formula	C10H14BClO2S
Molecular Weight	244.55 g/mol
Synonyms	5-Chloro-2-thienylboronic acid pinacol ester; 2-(5-Chlorothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chlorothiophene-2-boronic acid neopentyl glycol ester (common name); (5-Chlorothiophen-2-yl)boronic acid pinacol ester; Pinacol (5-chloro-2-thienyl)boronate; 5-Chloro-2-thiopheneboronic acid pinacol ester; CAS 635305-24-7
EINECS	Contact for details

Quality Control

Our 5-Chlorothiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.