Description

2-Pyrrolidinecarboxaldehyde, 3,4-Dihydroxy-, Phenylhydrazone, (2R,3R,4S)- (9Ci) is a stereochemically defined chiral compound, specifically a phenylhydrazone derivative of a dihydroxylated pyrrolidine aldehyde. This product is a valuable synthetic intermediate and building block for advanced organic synthesis, particularly in the development of pharmaceuticals and fine chemicals where precise stereochemistry is critical. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) due to its defined stereocenters and functional group diversity.
• Asymmetric Catalyst Ligand Precursor: Can be utilized in the development of chiral ligands for metal-catalyzed asymmetric reactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value organic compounds.
• Academic Research: A valuable reagent for university and institutional research in organic synthesis and stereochemistry studies.
• Bioconjugate Chemistry: Potential use in creating labeled probes or modified biomolecules via its reactive hydrazone functionality.

Basic Information

Product Name	2-Pyrrolidinecarboxaldehyde, 3,4-Dihydroxy-, Phenylhydrazone, (2R,3R,4S)- (9Ci)
CAS No.	634583-09-8
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	(2R,3R,4S)-3,4-Dihydroxy-2-formylpyrrolidine phenylhydrazone; (2R,3R,4S)-3,4-Dihydroxypyrrolidine-2-carboxaldehyde phenylhydrazone; (2R,3R,4S)-2-Pyrrolidinecarboxaldehyde, 3,4-dihydroxy-, phenylhydrazone; 3,4-Dihydroxy-L-proline aldehyde phenylhydrazone (stereospecific); L-threo-3,4-Dihydroxypyrrolidine-2-carbaldehyde phenylhydrazone; Phenylhydrazone of (2R,3R,4S)-3,4-dihydroxy-2-pyrrolidinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and development applications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are available upon request. Our quality management system ensures traceability and consistency for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.