Description

1-(2-Chloro-4-Methoxyphenyl)Ethan-1-Amine is a versatile chiral amine building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and methoxy substituents on the aromatic ring, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate for specialty chemicals, dyes, and advanced material precursors.
• Academic & R&D: Employed in methodological research for new synthetic routes and compound library generation.

Basic Information

Product Name	1-(2-Chloro-4-Methoxyphenyl)Ethan-1-Amine
CAS No.	634149-56-7
Molecular Formula	C9H12ClNO
Molecular Weight	185.65 g/mol
Synonyms	1-(2-Chloro-4-methoxyphenyl)ethanamine; α-Methyl-2-chloro-4-methoxyphenylamine; (R/S)-1-(2-Chloro-4-methoxyphenyl)ethylamine; 2-Chloro-4-methoxy-α-methylbenzylamine; 1-(2-Chloro-4-methoxyphenyl)ethylamine; 2-Chloro-4-methoxy-α-methylbenzylamine; 1-Amino-1-(2-chloro-4-methoxyphenyl)ethane
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-4-Methoxyphenyl)Ethan-1-Amine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.