Description

n-Methyl-2-(Trifluoromethyl)Benzenesulfonamide is a specialized organosulfur compound featuring a trifluoromethylated aromatic ring and a sulfonamide functional group. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly where the introduction of fluorine atoms is desired to modulate the properties of target molecules. It is primarily needed by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, especially protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, coatings, and liquid crystals.
• Chemical Research & Development: Employed as a versatile reagent for introducing sulfonamide and fluorinated aromatic motifs in complex molecule construction.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the reactivity and effects of the trifluoromethyl group adjacent to a sulfonamide.

Basic Information

Product Name	n-Methyl-2-(Trifluoromethyl)Benzenesulfonamide
CAS No.	633697-56-0
Molecular Formula	C9H8F3NO2S
Molecular Weight	239.22 g/mol
Synonyms	N-Methyl-2-(trifluoromethyl)benzenesulfonamide; 2-(Trifluoromethyl)-N-methylbenzenesulfonamide; Benzenesulfonamide, N-methyl-2-(trifluoromethyl)-; α,α,α-Trifluoro-o-toluenesulfonmethylamide; N-Methyl-α,α,α-trifluoro-o-toluenesulfonamide; o-(Trifluoromethyl)-N-methylbenzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-Methyl-2-(Trifluoromethyl)Benzenesulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.