Description

1-(4-Iodophenyl)Cyclobutanecarboxylic Acid is a high-purity iodinated cyclobutane derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its unique structural framework, which combines a rigid cyclobutane ring with a halogenated aromatic system, enabling precise molecular construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry programs targeting novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the iodophenyl moiety can be leveraged for further functionalization.
• Ligand & Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Potential monomer or additive in the research of advanced polymeric materials with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific halogenated scaffold.

Basic Information

Product Name	1-(4-Iodophenyl)Cyclobutanecarboxylic Acid
CAS No.	630382-89-7
Molecular Formula	C11H11IO2
Molecular Weight	302.11 g/mol
Synonyms	4-(1-Carboxycyclobutyl)iodobenzene; 1-(p-Iodophenyl)cyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 1-(4-iodophenyl)-; 1-(4-Iodophenyl)-1-cyclobutanecarboxylic Acid; 1-(4-Iodobenzene)Cyclobutanecarboxylic Acid; 4-(Cyclobutane-1-carbonyl)iodobenzene; p-Iodophenylcyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(4-Iodophenyl)Cyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Specifications can be tailored to meet specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.