Description

Cyclohexanone, 2-Hydroxy-2,3,4-Trimethyl-, (3S,4R)- (9Ci) is a high-purity, stereochemically defined derivative of cyclohexanone, serving as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry at the 3 and 4 positions makes it an invaluable intermediate for the production of complex, optically active molecules. This compound is essential for research and development in the pharmaceutical and fine chemical industries, where it is used to construct key structural motifs for active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in developing central nervous system (CNS) agents and anti-infectives.
• Asymmetric Catalysis Research: Used as a starting material or ligand precursor in the development of new stereoselective catalytic reactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Development: Acts as a building block for creating novel, stereospecific pesticides and herbicides with enhanced activity and selectivity.
• Academic & Industrial R&D: Serves as a standard or reagent in methodological studies and process chemistry optimization within organic chemistry laboratories.

Basic Information

Product Name	Cyclohexanone, 2-Hydroxy-2,3,4-Trimethyl-, (3S,4R)- (9Ci)
CAS No.	627460-70-2
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(3S,4R)-2-Hydroxy-2,3,4-trimethylcyclohexanone; 2,3,4-Trimethyl-2-hydroxycyclohexanone; (3S,4R)-2,3,4-Trimethyl-2-hydroxycyclohexanone; (3S,4R)-2-Hydroxy-2,3,4-trimethylcyclohexan-1-one; Cyclohexanone, 2-hydroxy-2,3,4-trimethyl-, (3S,4R)-; (3S,4R)-2-Hydroxy-2,3,4-trimethylcyclohexanone (9CI)
EINECS	Contact for details

Quality Control

Our production of Cyclohexanone, 2-Hydroxy-2,3,4-Trimethyl-, (3S,4R)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, and NMR to confirm identity, stereochemical purity, and chemical assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.