Description

2H-1-Benzopyran-5-Carboxylicacid,3-Amino-3,4-Dihydro-,Methylester,(3S)-(9Ci) is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the areas of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in the construction of complex molecular architectures requiring the specific (3S) stereochemistry.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Pre-clinical Development: Employed in the synthesis of candidate compounds for pharmacological evaluation.
• Chemical Reference Standard: Utilized as an analytical standard for method development and quality control in related synthetic pathways.

Basic Information

Product Name	2H-1-Benzopyran-5-Carboxylicacid,3-Amino-3,4-Dihydro-,Methylester,(3S)-(9Ci)
CAS No.	627099-61-0
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	(3S)-3-Amino-3,4-dihydro-2H-1-benzopyran-5-carboxylic acid methyl ester; Methyl (3S)-3-amino-3,4-dihydro-2H-chromene-5-carboxylate; (S)-Methyl 3-amino-3,4-dihydro-2H-chromene-5-carboxylate; (3S)-3-Amino-3,4-dihydro-2H-chromene-5-carboxylic acid methyl ester; (S)-3-Amino-3,4-dihydro-2H-1-benzopyran-5-carboxylic acid methyl ester; 627099-61-0; (3S)-Amino dihydro benzopyran carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity (enantiomeric excess), chemical purity by HPLC, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.