Description

2,2-Dimethylpyrrolidine Hydrochloride is a high-purity organic salt, serving as a critical chiral building block and intermediate in advanced chemical synthesis. Its value lies in providing a sterically hindered pyrrolidine scaffold, essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure contributes to efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.

Basic Information

Product Name	2,2-Dimethylpyrrolidine Hydrochloride
CAS No.	623580-01-8
Molecular Formula	C6H14ClN
Molecular Weight	135.64 g/mol
Synonyms	2,2-Dimethylpyrrolidine HCl; 2,2-Dimethylpyrrolidinium Chloride; Pyrrolidine, 2,2-dimethyl-, hydrochloride; 2,2-Dimethyl-1-azacyclopentane Hydrochloride; 2,2-Dimethylpyrrolidine Hydrochloride Salt; 2,2-Dimethylpyrrolidine Monohydrochloride; 2,2-DMP-HCl
EINECS	Contact for details

Quality Control

Our 2,2-Dimethylpyrrolidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical applications, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.