Description

(S)-n-[(1E)-Ethylidene]-2-Methylpropane-2-Sulfinamide is a high-purity chiral sulfinamide building block, widely recognized for its critical role in asymmetric synthesis. This compound serves as a versatile and efficient chiral auxiliary or ligand, enabling the stereoselective construction of complex molecules with high enantiomeric purity. It is an essential intermediate for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise control over molecular chirality is paramount.

Application

• As a chiral auxiliary in the asymmetric synthesis of amines, amino acids, and amino alcohols.
• As a ligand or catalyst component in enantioselective metal-catalyzed transformations.
• Key intermediate in the research and development of active pharmaceutical ingredients (APIs).
• Building block for the synthesis of novel agrochemicals and fine chemicals.
• Use in methodological development for organic and medicinal chemistry research.
• Precursor for the preparation of other chiral sulfinamide derivatives and catalysts.

Basic Information

Product Name	(S)-n-[(1E)-Ethylidene]-2-Methylpropane-2-Sulfinamide
CAS No.	623168-99-0
Molecular Formula	C7H15NOS
Molecular Weight	161.26 g/mol
Synonyms	(S)-N-[(1E)-Ethylidene]-2-methylpropane-2-sulfinamide; (S,E)-N-(1-Propenyl)-2-methylpropane-2-sulfinamide; (S)-tert-Butanesulfinyl imine (from acetaldehyde); (S)-N-(1-Propenyl)-2-methyl-2-propanesulfinamide; (S)-N-[(E)-Ethylidene]-2-methylpropane-2-sulfinamide; (S)-2-Methyl-N-[(1E)-1-propenyl]-2-propanesulfinamide; Chiral Sulfinamide Auxiliary
EINECS	Contact for details

Quality Control

Our (S)-n-[(1E)-Ethylidene]-2-Methylpropane-2-Sulfinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR, and determination of chemical purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.