Description

Cyclohexanone, 2-Acetyl-2,5-Dimethyl-, (2R,5R)- (9Ci) is a high-purity, chiral diketone derivative of cyclohexanone, serving as a critical advanced intermediate in sophisticated organic syntheses. Its defined stereochemistry and functional groups make it a valuable building block for creating complex molecules with specific spatial orientations. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), especially in stereoselective synthesis.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex organic molecules in agrochemicals, dyes, and specialty polymers.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Flavor & Fragrance Industry: Potential intermediate in the synthesis of high-value aroma chemicals and musk compounds due to its ketone backbone.
• Academic & Industrial R&D: Employed in chemical research for methodological studies in organic synthesis and stereochemistry.
• Material Science: Can be utilized in the development of specialty monomers for advanced polymeric materials.

Basic Information

Product Name	Cyclohexanone, 2-Acetyl-2,5-Dimethyl-, (2R,5R)- (9Ci)
CAS No.	622367-57-1
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(2R,5R)-2-Acetyl-2,5-dimethylcyclohexanone; (2R,5R)-2,5-Dimethyl-2-acetylcyclohexanone; (2R,5R)-1-(2,5-Dimethyl-2-oxocyclohexyl)ethan-1-one; 2-Acetyl-2,5-dimethylcyclohexanone (stereoisomer); Chiral 2,5-Dimethyl-2-acetylcyclohexanone; (R,R)-2-Acetyl-2,5-dimethylcyclohexanone; (2R,5R)-2,5-Dimethyl-α-oxocyclohexaneethanone
EINECS	Contact for details

Quality Control

Our Cyclohexanone, 2-Acetyl-2,5-Dimethyl-, (2R,5R)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (2R,5R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.