Description

(R)-n-(2-Hydroxy-2-Methyl-1-Phenyl-Propyl)-4-Methyl-Benzenesulfonamide is a high-purity chiral sulfonamide compound of significant interest in advanced organic synthesis. This compound matters as a crucial chiral building block or resolving agent for the development of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for asymmetric synthesis and process chemistry applications.

Application

• As a chiral auxiliary or resolving agent in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• As a key synthetic intermediate in the research and development of novel therapeutic candidates.
• For use in method development and scale-up studies within process chemistry and manufacturing.
• In academic and industrial research exploring new catalytic systems or stereoselective transformations.
• As a reference standard or analytical reagent for quality control and chiral purity analysis.
• Potential application as a ligand precursor in the preparation of catalysts for enantioselective reactions.

Basic Information

Product Name	(R)-n-(2-Hydroxy-2-Methyl-1-Phenyl-Propyl)-4-Methyl-Benzenesulfonamide
CAS No.	620627-46-5
Molecular Formula	C18H23NO3S
Molecular Weight	333.45 g/mol
Synonyms	(R)-N-(2-Hydroxy-2-methyl-1-phenylpropyl)-4-methylbenzenesulfonamide; (R)-Toluenesulfonamide, N-(2-hydroxy-2-methyl-1-phenylpropyl)-; (R)-N-(2-Hydroxy-2-methyl-1-phenylpropyl)-p-toluenesulfonamide; (R)-α,α-Dimethyl-β-hydroxybenzenepropanamine N-p-tolylsulfonyl derivative; (R)-Benzenemethanamine, N-[(4-methylphenyl)sulfonyl]-α,α-dimethyl-β-hydroxy-; (R)-enantiomer of N-(2-Hydroxy-2-methyl-1-phenylpropyl)-4-methylbenzenesulfonamide
EINECS	Contact for details

Quality Control

Our (R)-n-(2-Hydroxy-2-Methyl-1-Phenyl-Propyl)-4-Methyl-Benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity, meeting the stringent requirements for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.