Description

Ethanone, 1-[(1R,3R)-3-Hydroxycyclohexyl]-, Rel- (9Ci) is a chiral, optically active ketone derivative featuring a hydroxycyclohexyl substituent, serving as a critical chiral building block and intermediate in advanced organic synthesis. This compound is valued for its defined stereochemistry, which is essential for imparting specific biological activity and physical properties in the final target molecules. It is primarily sought by R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents, anti-inflammatory drugs, and other therapeutic compounds where stereochemistry is crucial.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the specific spatial orientation of the molecule can enhance target specificity and environmental profile.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for the development of novel chiral ligands and catalysts used in enantioselective synthesis to produce other high-value, single-enantiomer compounds.
• Fragrance & Flavor Chemistry: Acts as an intermediate in the creation of complex, stereochemically-defined aroma chemicals and flavoring agents for high-end applications.
• Material Science Research: Investigated as a monomer or modifying agent for synthesizing polymers with specific chiral properties for advanced material applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	Ethanone, 1-[(1R,3R)-3-Hydroxycyclohexyl]-, Rel- (9Ci)
CAS No.	620158-59-0
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	rel-(1R,3R)-3-Acetylcyclohexanol; 1-[(1R,3R)-3-Hydroxycyclohexyl]ethanone; (1R,3R)-3-Hydroxycyclohexyl methyl ketone; rel-(1R,3R)-3-Hydroxycyclohexyl methyl ketone; (R,R)-3-Acetylcyclohexanol; Chiral 3-Acetylcyclohexanol; (1R,3R)-3-Acetyl-1-cyclohexanol
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1R,3R)-3-Hydroxycyclohexyl]-, Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high stereochemical purity. Quality is verified through comprehensive analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment. We support cGMP-compliant production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Optical Rotation [α]	Specified range provided on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.