Description

Pyrazine, 2-Methyl-5-(Tributylstannyl)- is a specialized organotin derivative of a methylpyrazine heterocycle, serving as a critical building block in advanced synthetic chemistry. This compound matters for its role as a versatile reagent in cross-coupling reactions, enabling the precise introduction of the pyrazine moiety into complex molecular architectures. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in constructing heterocyclic cores for potential therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyrazine ring contributes to biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel organometallic catalysts and ligands used in homogeneous catalysis.
• Cross-Coupling Reactions: Acts as a stamane reagent in Stille coupling reactions to form new carbon-carbon bonds with high selectivity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and mechanisms.

Basic Information

Product Name	Pyrazine, 2-Methyl-5-(Tributylstannyl)-
CAS No.	619331-61-2
Molecular Formula	C17H32N2Sn
Molecular Weight	383.16 g/mol
Synonyms	2-Methyl-5-(tributylstannyl)pyrazine; 5-(Tributylstannyl)-2-methylpyrazine; Tributyl(5-methylpyrazin-2-yl)stannane; 2-Methylpyrazine-5-tributyltin; Stannane, tributyl(5-methyl-2-pyrazinyl)-; (5-Methylpyrazin-2-yl)tributylstannane
EINECS	Contact for details

Quality Control

Our Pyrazine, 2-Methyl-5-(Tributylstannyl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production applications. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	30.0 - 32.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.