Description

C-(4-p-Tolyl-Tetrahydro-Pyran-4-Yl)-Methylamine is a specialized organic building block featuring a tetrahydro-pyran ring substituted with a tolyl and an aminomethyl group. This compound matters as a versatile chiral intermediate for the synthesis of complex molecules, offering a unique scaffold for pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its structural complexity for bioactivity.
• Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis, enhancing stereoselectivity in chemical reactions.
• Material Science: Intermediate for creating specialty polymers and advanced organic materials with specific functional properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	C-(4-p-Tolyl-Tetrahydro-Pyran-4-Yl)-Methylamine
CAS No.	619296-06-9
Molecular Formula	C14H21NO
Molecular Weight	219.32 g/mol
Synonyms	4-[(4-Methylphenyl)methyl]-4-(aminomethyl)tetrahydro-2H-pyran; (4-((4-Methylbenzyl)oxy)tetrahydro-2H-pyran-4-yl)methanamine; 4-(Aminomethyl)-4-(4-methylbenzyl)tetrahydro-2H-pyran; 4-(p-Tolylmethyl)-4-(aminomethyl)tetrahydro-2H-pyran; 4-(4-Methylbenzyl)-4-(aminomethyl)tetrahydropyran; C-(4-p-Tolyl-tetrahydro-pyran-4-yl)-methylamine; 619296-06-9; 4-(Aminomethyl)-4-[(4-methylphenyl)methyl]oxane
EINECS	Contact for details

Quality Control

Our C-(4-p-Tolyl-Tetrahydro-Pyran-4-Yl)-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.