Description

2-Bromo-4,6-Dimethylnicotinic Acid is a high-purity, halogenated nicotinic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized pyridine core that enables the construction of complex molecules with precise structural control. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the substituted pyridine moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical companies offering bespoke synthesis services for clients in R&D.

Basic Information

Product Name	2-Bromo-4,6-Dimethylnicotinic Acid
CAS No.	618397-77-6
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Bromo-4,6-dimethylpyridine-3-carboxylic acid; 3-Carboxy-2-bromo-4,6-dimethylpyridine; 4,6-Dimethyl-2-bromonicotinic acid; Nicotinic acid, 2-bromo-4,6-dimethyl-; 2-Bromo-4,6-lutidinic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,6-Dimethylnicotinic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.