Description

2H-Pyran-3(6H)-One, 6-Hydroxy-2-(Hydroxymethyl)-, (2S)- (9Ci) is a chiral, high-purity chemical intermediate of significant interest in advanced organic synthesis. Its value lies in its unique bicyclic lactol structure, which serves as a versatile building block for creating complex, stereochemically defined molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental profile.
• Fine Chemical Building Block: Employed in the construction of complex natural product analogs, flavors, fragrances, and specialty polymers requiring specific stereochemistry.
• Catalyst and Ligand Development: Serves as a precursor for novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Item	Details
Product Name	2H-Pyran-3(6H)-One, 6-Hydroxy-2-(Hydroxymethyl)-, (2S)- (9Ci)
CAS No.	617711-44-1
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	(2S)-6-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one; (S)-6-Hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one; (2S)-6-Hydroxy-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-one; (S)-6-Hydroxy-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-one; (S)-2-(Hydroxymethyl)-6-hydroxy-3,6-dihydro-2H-pyran-3-one; (2S)-2-(Hydroxymethyl)-6-hydroxy-3,6-dihydro-2H-pyran-3-one; (S)-Lactol derivative of 2H-pyran-3(6H)-one
EINECS	Contact for details

Quality Control

Our 2H-Pyran-3(6H)-One, 6-Hydroxy-2-(Hydroxymethyl)-, (2S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.