Description

cis-2-Methyloxolane-3-Carboxylic Acid (Wx611127) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique oxolane (tetrahydrofuran) ring structure fused with a carboxylic acid functionality, making it a versatile precursor for pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex stereochemistry into target molecules. The CAS number for this compound is 617690-26-3.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry for efficacy.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the oxolane moiety can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex fragrance compounds, flavors, and other high-value specialty chemicals.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, exploring new ring-forming reactions and stereoselective transformations.
• Material Science Precursor: Potential use in synthesizing monomers for specialized polymers with unique thermal or mechanical properties.

Basic Information

Item	Detail
Product Name	cis-2-Methyloxolane-3-Carboxylic Acid (Wx611127)
CAS No.	617690-26-3
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(3S,4R)-3-Methyltetrahydrofuran-4-carboxylic Acid; (3S,4R)-3-Methyloxolane-4-carboxylic Acid; cis-3-Methyltetrahydrofuran-4-carboxylic Acid; 2-Methyloxolane-3-carboxylic Acid; WX-611127; Wx611127
EINECS	Contact for details

Quality Control

Every batch of cis-2-Methyloxolane-3-Carboxylic Acid is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and chiral integrity meet the exacting standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.