Description

2H-Pyran-2-One,Tetrahydro-4-Hydroxy-5-Methyl-6-(1-Methylethyl)-,(4S,5R,6S)-(9Ci) is a high-purity, stereochemically defined lactone derivative with significant utility in advanced organic synthesis. This compound matters as a versatile chiral building block, enabling the construction of complex molecular architectures with precise stereocontrol. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications ranging from medicinal chemistry to the synthesis of natural product analogs and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for compounds with lactone or polyketide-like frameworks.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific pesticides and herbicides where the defined stereochemistry is crucial for biological activity.
• Fine Chemical Production: Acts as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring specific enantiomeric purity.
• Academic & Industrial Research: Employed as a model compound or starting material in methodological studies for asymmetric synthesis and catalysis.
• Material Science: Potential monomer or modifier for the synthesis of biodegradable polymers or polymers with specific optical properties.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-4-Hydroxy-5-Methyl-6-(1-Methylethyl)-,(4S,5R,6S)-(9Ci)
CAS No.	616207-71-7
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(4S,5R,6S)-Tetrahydro-4-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-one; (4S,5R,6S)-4-Hydroxy-5-methyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; Stereoisomer of whisky lactone; Oak lactone isomer; 5-Methyl-6-(1-methylethyl)-4-hydroxy-tetrahydro-2H-pyran-2-one (specified stereochemistry); Chiral γ-lactone derivative; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2H-Pyran-2-One,Tetrahydro-4-Hydroxy-5-Methyl-6-(1-Methylethyl)-,(4S,5R,6S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (4S,5R,6S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.