Description

cis-2,4,5-Tris(4-Fluorophenyl)Imidazoline CAS NO 612808-11-4 is a specialized fluorinated heterocyclic compound belonging to the imidazoline class. This high-value intermediate is critical for advanced research and development in pharmaceutical and agrochemical synthesis. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for constructing complex molecules with tailored biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorophenyl groups enhance bioavailability and environmental stability.
• Ligand & Catalyst Development: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive for developing advanced polymers with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	cis-2,4,5-Tris(4-Fluorophenyl)Imidazoline
CAS No.	612808-11-4
Molecular Formula	C21H15F3N2
Molecular Weight	352.35 g/mol
Synonyms	2,4,5-Tris(4-fluorophenyl)-4,5-dihydro-1H-imidazole; 2,4,5-Tris(p-fluorophenyl)-2-imidazoline; 1H-Imidazole, 4,5-dihydro-2,4,5-tris(4-fluorophenyl)-, (4R,5S)-rel-; cis-2,4,5-Tri(4-fluorophenyl)imidazolidine; 4,5-Dihydro-2,4,5-tris(4-fluorophenyl)-1H-imidazole; 2,4,5-Tris(4-fluorophenyl)-4,5-dihydroimidazole
EINECS	Contact for details

Quality Control

Our cis-2,4,5-Tris(4-Fluorophenyl)Imidazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for advanced intermediate production upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.