Description

7-Bromo-2,3-dihydropyrano[2,3-b]quinoline is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound matters as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly in the areas of oncology and central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex polycyclic and heterocyclic compounds due to its reactive bromine substituent and fused ring system.
• Agrochemical Development: Potential application as an intermediate in the synthesis of new crop protection agents and herbicides.
• Material Science Research: Investigated for the development of organic electronic materials and fluorescent dyes, leveraging its quinoline-based chromophore.

Basic Information

Product Name	7-Bromo-2,3-dihydropyrano[2,3-b]quinoline
CAS No.	612494-86-7
Molecular Formula	C₁₄H₁₀BrNO
Molecular Weight	288.14 g/mol
Synonyms	7-Bromo-2,3-dihydro-4H-pyrano[2,3-b]quinoline; 7-Bromo-2,3-dihydro-4H-pyrano[2,3-b]quinoline; 7-Bromo-4H-pyrano[2,3-b]quinoline, 2,3-dihydro-; 612494-86-7; Pyrano[2,3-b]quinoline, 7-bromo-2,3-dihydro-; SCHEMBL21842527; BRN 1234567 (Example)
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-dihydropyrano[2,3-b]quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.