Description

2-Methylthio-5-(Tributylstannyl)Pyridine is a specialized organotin reagent featuring a pyridine core functionalized with a methylthio group and a tributylstannyl moiety. This compound is a critical building block in modern synthetic organic chemistry, particularly for Stille cross-coupling reactions, enabling the efficient construction of complex heterocyclic systems. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used to create novel pesticides, herbicides, and fungicides by introducing the pyridyl-stannane unit into complex molecular architectures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic semiconductors, conductive polymers, and liquid crystals.
• Stille Coupling Reagent: A versatile organometallic reagent for forming carbon-carbon bonds between the stannyl group and various organic electrophiles like aryl halides or triflates.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research.
• Catalyst Ligand Precursor: Can be modified to create novel ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Methylthio-5-(Tributylstannyl)Pyridine
CAS No.	611168-64-0
Molecular Formula	C18H33NSSn
Molecular Weight	414.22 g/mol
Synonyms	5-(Tributylstannyl)-2-(methylthio)pyridine; 2-(Methylthio)-5-(tributylstannyl)pyridine; Tributyl(5-(methylthio)pyridin-2-yl)stannane; 2-Methylmercapto-5-tributylstannylpyridine; Pyridine, 2-(methylthio)-5-(tributylstannyl)-; Stannane, tributyl[5-(methylthio)-2-pyridinyl]-; 2-Methylsulfanyl-5-tributylstannanylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Methylthio-5-(Tributylstannyl)Pyridine is produced and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C/59-77°F) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or ambient light should be avoided. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	28.5 - 29.5 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.