Description

1-Isopropylcyclobutanecarboxylic Acid is a specialized cyclobutane derivative carboxylic acid, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique sterically hindered structure makes it particularly useful for constructing complex molecular architectures with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is employed in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the synthesis of sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Intermediate for creating specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes and inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1-Isopropylcyclobutanecarboxylic Acid
CAS No.	610791-04-3
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	1-(1-Methylethyl)cyclobutanecarboxylic Acid; Isopropylcyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 1-(1-methylethyl)-; 1-Isopropyl-cyclobutanecarboxylic acid; 1-Propan-2-ylcyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Isopropylcyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.