Description

6-Amino-3-Methyl-4-(5-Phenylfuran-2-Yl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates, especially within medicinal chemistry programs focused on pyrazole and pyranopyrazole derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new drug molecules, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) due to its functionalized pyranopyrazole core.
• Biochemical Tool Compound: Acts as a research chemical for investigating biological pathways and enzyme interactions in academic and industrial settings.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for advanced material science applications.

Basic Information

Product Name	6-Amino-3-Methyl-4-(5-Phenylfuran-2-Yl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	609335-60-6
Molecular Formula	C₁₈H₁₄N₄O₂
Molecular Weight	318.33 g/mol
Synonyms	6-Amino-3-methyl-4-(5-phenyl-2-furanyl)-1,4-dihydro-5-cyano-pyrano[2,3-c]pyrazole; 6-Amino-3-methyl-4-(5-phenylfuran-2-yl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydro-6-amino-3-methyl-4-(5-phenyl-2-furanyl)-5-cyano-pyrano[2,3-c]pyrazole; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-1,4-dihydro-3-methyl-4-(5-phenyl-2-furanyl)-; 609335-60-6; 4-(5-Phenylfuran-2-yl)-6-amino-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Methyl-4-(5-Phenylfuran-2-Yl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.