Description

(S)-2,4,6-Trimethylbenzenesulfinamide is a high-purity chiral sulfinamide building block, a critical intermediate in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and ligand for the stereoselective construction of carbon-nitrogen and carbon-carbon bonds, enabling the production of enantiomerically pure pharmaceuticals and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients with high optical purity.

Application

• Asymmetric Synthesis: Employed as a chiral auxiliary in the stereoselective synthesis of amines, amino acids, and other nitrogen-containing compounds.
• Pharmaceutical Intermediates: A key building block for the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other targeted therapies.
• Catalyst and Ligand Preparation: Used in the synthesis of chiral catalysts and ligands for transition metal-catalyzed reactions, such as asymmetric oxidations and reductions.
• Agrochemical Research: Serves as a precursor in the development of chiral herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new routes in complex molecule synthesis.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(S)-2,4,6-Trimethylbenzenesulfinamide
CAS No.	607729-50-0
Molecular Formula	C9H13NOS
Molecular Weight	183.27 g/mol
Synonyms	(S)-2,4,6-Trimethylbenzenesulfinamide; (S)-Mesitylenesulfinamide; (S)-2,4,6-Trimethylphenylsulfinamide; (S)-Mesitylsulfinamide; (S)-Benzenesulfinamide, 2,4,6-trimethyl-; (S)-Toluenesulfinamide, 2,4,6-trimethyl-; (S)-Sulfinylamine, N-(2,4,6-trimethylphenyl)-
EINECS	Contact for details

Quality Control

Our (S)-2,4,6-Trimethylbenzenesulfinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep container tightly sealed under an inert gas (nitrogen or argon) when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.