Description

2H-Pyran-2-One, Tetrahydro-3-(Trifluoroacetyl)- (9Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of a trifluoroacetyl group can dramatically alter biological activity and metabolic stability. Industries that require high-purity, novel intermediates for research and process development, such as medicinal chemistry and fine chemical manufacturing, are the primary users of this material.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced potency.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoroacetyl moiety can improve lipophilicity and environmental stability.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers and coatings with unique thermal or chemical resistance properties.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research focused on exploring new fluorination methodologies and the synthesis of complex fluoroorganic compounds.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	2H-Pyran-2-One, Tetrahydro-3-(Trifluoroacetyl)- (9Ci)
CAS No.	606491-90-1
Molecular Formula	C7H7F3O3
Molecular Weight	196.13 g/mol
Synonyms	3-(Trifluoroacetyl)dihydro-2H-pyran-2-one; Tetrahydro-3-(trifluoroacetyl)-2H-pyran-2-one; 3-Trifluoroacetyl-tetrahydro-pyran-2-one; Dihydro-3-(trifluoroacetyl)-2H-pyran-2(3H)-one; 2H-Pyran-2-one, tetrahydro-3-(trifluoroacetyl)-; 606491-90-1; 3-Trifluoroacetyl-3,4,5,6-tetrahydro-2H-pyran-2-one
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-2-One, Tetrahydro-3-(Trifluoroacetyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.