Description

Phenylalanine, 2-Ethoxy- (9Ci) CAS NO 603105-66-4 is a specialized derivative of the essential amino acid phenylalanine, characterized by an ethoxy substitution at the 2-position. This structural modification imparts unique physicochemical properties, making it a valuable non-natural amino acid building block for advanced research and synthesis. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel peptides, bioactive compounds, and complex organic molecules. The compound's specific stereochemistry and functional group are critical for applications requiring precise molecular design.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based therapeutics.
• Peptide Synthesis: Used as a modified amino acid residue in solid-phase and solution-phase peptide synthesis to introduce specific functionalities and alter peptide stability or bioavailability.
• Biochemical Research: Employed in metabolic pathway studies, enzyme substrate specificity investigations, and as a probe in biochemical assays.
• Agrochemical Development: Acts as a precursor or intermediate in the synthesis of advanced crop protection agents and plant growth regulators.
• Material Science: Potential building block for specialty polymers and advanced materials where amino acid-based monomers are required.
• Academic & Industrial R&D: A critical reagent for synthetic organic chemists in universities and corporate labs exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	Phenylalanine, 2-Ethoxy- (9Ci)
CAS No.	603105-66-4
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	2-Ethoxyphenylalanine; O-Ethyl-L-tyrosine; 2-Ethoxy-L-phenylalanine; (2S)-2-Amino-3-(2-ethoxyphenyl)propanoic acid; Ethoxytyrosine; L-2-Ethoxyphenylalanine; 2-ethoxy-DL-phenylalanine; 603105-66-4
EINECS	Contact for details

Quality Control

Our Phenylalanine, 2-Ethoxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of related substances. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%
Solubility	Soluble in common organic solvents (e.g., DMSO, methanol); sparingly soluble in water.

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.