Description

Cyclopenta[C]Pyran-3(1H)-One, Hexahydro-6-Methoxy-, (4Ar,6S,7Ar)-Rel- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical chiral building block in the synthesis of complex, biologically active molecules, offering precise control over the final product's stereochemistry and efficacy. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries working on novel therapeutic agents, particularly in areas requiring sophisticated molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct complex molecular frameworks with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and other high-value compounds requiring specific stereochemistry.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic organic chemistry research.

Basic Information

Product Name	Cyclopenta[C]Pyran-3(1H)-One, Hexahydro-6-Methoxy-, (4Ar,6S,7Ar)-Rel- (9Ci)
CAS No.	600700-66-1
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	rel-(4aR,6S,7aR)-Hexahydro-6-methoxycyclopenta[c]pyran-3(1H)-one; Hexahydro-6-methoxycyclopenta[c]pyran-3(1H)-one, (4aR,6S,7aR)-rel-; (rel)-(4aR,6S,7aR)-6-Methoxyhexahydrocyclopenta[c]pyran-3(1H)-one; Advanced Chiral Lactone Intermediate; 6-Methoxyhexahydrocyclopenta[c]pyran-3(1H)-one (relative stereochemistry specified).
EINECS	Contact for details

Quality Control

Our Cyclopenta[C]Pyran-3(1H)-One, Hexahydro-6-Methoxy-, (4Ar,6S,7Ar)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.