Description

(Z)-1,2-Diphenyl-1-(4-Hydroxyphenyl)-1-Butene CAS NO 69967-80-2 is a high-purity, non-steroidal triphenylethylene derivative with a defined stereochemistry. This compound serves as a critical pharmaceutical intermediate and a valuable research chemical for the development of selective estrogen receptor modulators (SERMs). It is essential for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular building blocks for therapeutic and investigative applications.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the manufacture of selective estrogen receptor modulators (SERMs) and related therapeutic agents.
• Biochemical Research: Used as a reference standard and probe compound in studies of estrogen receptor binding, signaling pathways, and endocrine system interactions.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex organic molecules with specific stereochemical and functional group properties.
• Academic & Industrial R&D: Employed in discovery chemistry programs targeting hormone-related conditions, including oncology and metabolic disorders.
• Analytical Standard: Utilized for method development, calibration, and quality control in HPLC, LC-MS, and other analytical techniques within QC laboratories.

Basic Information

Product Name	(Z)-1,2-Diphenyl-1-(4-Hydroxyphenyl)-1-Butene
CAS No.	69967-80-2
Molecular Formula	C28H24O
Molecular Weight	376.49 g/mol
Synonyms	(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene; (Z)-1-(4-Hydroxyphenyl)-1,2-diphenyl-1-butene; Z-Endoxifen; (Z)-Endoxifen; (Z)-4-Hydroxy-N-desmethyltamoxifen; (Z)-4-OH-N-des-TAM; cis-Endoxifen; (Z)-Isomer of 1,2-Diphenyl-1-(4-Hydroxyphenyl)-1-Butene
EINECS	Contact for details

Quality Control

Our (Z)-1,2-Diphenyl-1-(4-Hydroxyphenyl)-1-Butene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.