Description

(5'S)-3α-[[Dimethyl(Pentafluorophenyl)Silyl]Oxy]-2',2',5'-Trimethylspiro[5β-Androstane-17,4'-[1,3]Dioxa[2]Silacyclopentane] is a highly specialized organosilicon derivative of an androstane steroid, designed for advanced synthetic and research applications. This compound is valued for its role as a protected intermediate or chiral building block in complex organic synthesis, particularly in pharmaceutical development. It is primarily utilized by research institutions and industrial R&D departments focused on steroid chemistry, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a building block for constructing complex molecular libraries to study structure-activity relationships (SAR) and biological activity.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value steroid derivatives.
• Asymmetric Synthesis: Leverages its defined stereochemistry for the synthesis of enantiomerically pure compounds in academic and industrial research.
• Reference Standard: Can be used as an analytical standard for method development and quality control in steroid analysis.
• Material Science Precursor: Potential use in the development of advanced organic-inorganic hybrid materials due to its silane functional group.

Basic Information

Product Name	(5'S)-3α-[[Dimethyl(Pentafluorophenyl)Silyl]Oxy]-2',2',5'-Trimethylspiro[5β-Androstane-17,4'-[1,3]Dioxa[2]Silacyclopentane]
CAS No.	69745-69-3
Molecular Formula	C32H43F5O3Si2
Molecular Weight	638.85 g/mol
Synonyms	3α-[(Dimethyl(pentafluorophenyl)silyl)oxy]-2,2,5-trimethylspiro[5α-androstane-17,4'-[1,3]dioxa[2]silacyclopentane]; (5'S)-3α-[[Dimethyl(pentafluorophenyl)silyl]oxy]-2',2',5'-trimethylspiro[5β-androstane-17,4'-[1,3]dioxa[2]silacyclopentane]; Androstane silyl ether derivative; Pentafluorophenylsilyl-protected androstane; Steroid silyl ether; CAS 69745-69-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for each lot are available upon request. We adhere to a cGMP-compliant quality management system suitable for the production of research and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.