Description

2-Chloro-4-(Trifluoromethoxy)Aniline is a high-purity, versatile aromatic amine building block characterized by its unique trifluoromethoxy and chloro substituents. This compound matters for its critical role as a key intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development teams in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A crucial precursor for synthesizing herbicides, fungicides, and insecticides, leveraging the aniline moiety for bioactivity.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), particularly in molecules requiring fluorinated aromatic systems.
• Dye and Pigment Synthesis: Serves as a starting material for producing specialized azo dyes and organic pigments.
• Liquid Crystal & OLED Materials: Employed in the synthesis of advanced electronic materials for displays and optoelectronic devices.
• Polymer Modification: Acts as a functional monomer or curing agent in the production of specialty polymers and resins.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex molecular architectures.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethoxy)Aniline
CAS No.	69695-61-0
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	2-Chloro-4-(trifluoromethoxy)benzenamine; 2-Chloro-α,α,α-trifluoro-p-anisidine; 4-Amino-3-chlorophenyl trifluoromethyl ether; Benzenamine, 2-chloro-4-(trifluoromethoxy)-; 3-Chloro-4-aminophenyl trifluoromethyl ether; 2-Chloro-4-trifluoromethoxyaniline; 2-Chloro-4-(trifluoromethoxy)phenylamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethoxy)Aniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.