Description

(17α)-20-(Methoxyimino)-3,11β,21-Tris(Trimethylsiloxy)Pregna-3,5-Dien-18-Al o-Methyl Oxime is a high-purity, advanced pharmaceutical intermediate characterized by its complex steroidal structure with multiple protective silyl ether groups. This compound is critical for research and development in synthetic organic chemistry, particularly in the synthesis of novel steroid-based therapeutics and fine chemicals. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for use in complex multi-step synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-derived active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Used in academic and industrial R&D for developing new synthetic methodologies and exploring structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for the production of complex steroid molecules.
• Biochemical Research: Utilized in studies investigating steroid hormone pathways and receptor interactions due to its modified pregnane backbone.

Basic Information

Product Name	(17α)-20-(Methoxyimino)-3,11β,21-Tris(Trimethylsiloxy)Pregna-3,5-Dien-18-Al o-Methyl Oxime
CAS No.	69688-41-1
Molecular Formula	C₃₃H₆₁NO₆Si₃
Molecular Weight	660.1 g/mol
Synonyms	20-(Methoxyimino)-3,11β,21-tris(trimethylsiloxy)pregna-3,5-dien-18-al O-methyloxime; Pregna-3,5-dien-18-al, 20-(methoxyimino)-3,11,21-tris[(trimethylsilyl)oxy]-, O-methyloxime; 3,11β,21-Tris-O-(trimethylsilyl)-20-(methoxyimino)pregna-3,5-dien-18-al O-methyloxime; Steroid Silyl Ether Intermediate; TMS-protected Pregnadienone Oxime Derivative
EINECS	Contact for details

Quality Control

Our (17α)-20-(Methoxyimino)-3,11β,21-Tris(Trimethylsiloxy)Pregna-3,5-Dien-18-Al o-Methyl Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.