Description

(6E)-3β-[(Dichloromethyl)Dimethylsiloxy]-9,10-Secocholesta-5(10),6,8(14)-Triene CAS NO 69688-11-5 is a high-purity, organosilicon-modified steroidal intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a versatile building block in the development of novel pharmaceutical agents and bioactive molecules, enabling precise structural modifications. It is primarily needed by research institutions and pharmaceutical companies engaged in steroid chemistry, drug discovery, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel steroid-based therapeutics and hormone analogs.
• Research & Development: Used in academic and industrial R&D for exploring new chemical entities and reaction pathways in steroid chemistry.
• Organic Synthesis Building Block: Serves as a specialized synthon for introducing the unique secosteroid framework with organosilicon functionality into target molecules.
• Biochemical Probe Development: Potential use in creating labeled or modified sterols for studying biological membrane interactions and enzyme mechanisms.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, complex fine chemicals and specialty materials.

Basic Information

Product Name	(6E)-3β-[(Dichloromethyl)Dimethylsiloxy]-9,10-Secocholesta-5(10),6,8(14)-Triene
CAS No.	69688-11-5
Molecular Formula	C30H48Cl2OSi
Molecular Weight	515.70 g/mol
Synonyms	3β-[(Dichloromethyl)dimethylsilyloxy]-9,10-secocholesta-5(10),6,8(14)-triene; (6E)-3β-[(Dichloromethyl)dimethylsiloxy]-9,10-secocholesta-5(10),6,8(14)-triene; 9,10-Secocholesta-5(10),6,8(14)-trien-3-ol, 3-[(dichloromethyl)dimethylsilyl] ether, (3β,6E)-; Steroid silyl ether intermediate; Organosilicon steroid derivative; Secosteroid silyl ether; CAS 69688-11-5
EINECS	Contact for details

Quality Control

Our (6E)-3β-[(Dichloromethyl)Dimethylsiloxy]-9,10-Secocholesta-5(10),6,8(14)-Triene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full spectroscopic data are provided to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.