Description

6-Fluoro-4-Chromanone Hydantoin is a fluorinated heterocyclic compound that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic incorporation of both fluorine and the hydantoin moiety, which are critical for modulating the biological activity and physicochemical properties of target molecules. This high-purity building block is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the hydantoin ring.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies and library synthesis.
• Advanced Material Precursor: Potential use in the synthesis of specialized polymers or ligands for catalytic systems, leveraging its rigid, fused-ring structure.

Basic Information

Product Name	6-Fluoro-4-Chromanone Hydantoin
CAS No.	69684-83-9
Molecular Formula	C₁₂H₉FN₂O₃
Molecular Weight	248.21 g/mol
Synonyms	6-Fluoro-4-oxo-4H-chromene-3-carboxylic acid hydantoin; 6-Fluoro-4-oxochroman-3-carboxylic acid hydantoin; 6-Fluoro-4-chromanone-3-hydantoin; 3-(6-Fluoro-4-oxochroman-3-carbonyl)imidazolidine-2,4-dione; 6-Fluoro-3-(2,4-dioxoimidazolidin-3-yl)carbonyl-4-chromanone
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Chromanone Hydantoin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports applications requiring high-purity intermediates under GMP-like controls for non-pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.