Description

Cyclobutanol,2-Amino-1-Methyl-,cis-(-)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters because its unique cis-fused cyclobutane ring with amino and methyl substituents provides a rigid, three-dimensional scaffold for constructing complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical R&D teams for applications such as the development of novel active pharmaceutical ingredients (APIs), chiral ligands, and other fine chemicals where precise stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule enhances efficacy.
• Chiral Catalyst & Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical & Specialty Material Production: Employed in the synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, particularly in ring-strain chemistry and stereoselective transformations.

Basic Information

Product Name	Cyclobutanol,2-Amino-1-Methyl-,cis-(-)-(9Ci)
CAS No.	69632-91-3
Molecular Formula	C5H11NO
Molecular Weight	101.15 g/mol
Synonyms	cis-(-)-2-Amino-1-methylcyclobutanol; (1R,2S)-2-Amino-1-methylcyclobutanol; (-)-cis-2-Amino-1-methylcyclobutanol; 2-Amino-1-methyl-cis-cyclobutanol; 1-Methyl-2-aminocyclobutanol (cis-); Amino-methylcyclobutanol; Chiral cyclobutanol amine; 9CI compound 69632-91-3
EINECS	Contact for details

Quality Control

Our Cyclobutanol,2-Amino-1-Methyl-,cis-(-)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (NMR, IR, MS) are provided to guarantee identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.