Description

Benzaldehde-0-(4,4,6-Trimethyl-[1,3,2]-Dioxaborinan-2-Yl)-Oxime is a specialized organoboron compound, specifically a boronic ester derivative of a benzaldehyde oxime. This chemical matters as a versatile synthetic intermediate, offering a protected boronic acid functionality that is crucial for modern cross-coupling reactions in pharmaceutical and advanced materials research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of aryl groups.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Can be utilized as a reagent for bioconjugation or as a handle in the synthesis of activity-based probes and inhibitors.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis studies within university and corporate laboratories.
• Ligand Synthesis: Acts as a starting material for the preparation of novel ligands used in homogeneous catalysis.

Basic Information

Product Name	Benzaldehde-0-(4,4,6-Trimethyl-[1,3,2]-Dioxaborinan-2-Yl)-Oxime
CAS No.	69583-68-2
Molecular Formula	C₁₄H₂₀BNO₃
Molecular Weight	261.12 g/mol
Synonyms	Benzaldehyde O-(4,4,6-Trimethyl-1,3,2-dioxaborinan-2-yl)oxime; 4,4,6-Trimethyl-2-[(E)-(phenylmethylene)amino]oxy]-1,3,2-dioxaborinane; Benzaldoxime O-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl) ether; (Benzaldehyde oxime) boronic ester pinacol variant; (E)-Benzaldehyde O-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)oxime; N-[(4,4,6-Trimethyl-1,3,2-dioxaborinan-2-yl)oxy]benzenecarboximidoyl
EINECS	Contact for details

Quality Control

Our Benzaldehde-0-(4,4,6-Trimethyl-[1,3,2]-Dioxaborinan-2-Yl)-Oxime is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent performance for sensitive synthetic applications. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR	Conforms to structure
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.