Description

S-(3-Chloro-2-Methyl-3-Oxopropyl) (S)-Ethanethioate is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring both a thioester and a reactive chloro-ketone moiety, makes it a valuable precursor for constructing complex, sulfur-containing molecules with defined stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of proprietary drug candidates, particularly those requiring sulfur-based functional groups.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its specific stereochemistry can influence biological activity.
• Asymmetric Synthesis: Serves as a versatile electrophile or building block in stereoselective reactions to create complex, optically active molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high-purity chiral intermediates.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	S-(3-Chloro-2-Methyl-3-Oxopropyl) (S)-Ethanethioate
CAS No.	69570-39-4
Molecular Formula	C6H9ClO2S
Molecular Weight	180.65 g/mol
Synonyms	(S)-S-(3-Chloro-2-methyl-3-oxopropyl) ethanethioate; (S)-3-(Acetylthio)-2-methylpropionyl chloride (tautomeric form); 3-Chloro-2-methyl-3-oxopropyl thioacetate, (S)-; 2-Methyl-3-oxo-3-chloropropyl thioacetate; Acetic acid, 3-chloro-2-methyl-3-oxopropyl ester, (S)-; 69570-39-4; Chiral chloro-ketone thioester.
EINECS	Contact for details

Quality Control

Our production of S-(3-Chloro-2-Methyl-3-Oxopropyl) (S)-Ethanethioate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm identity, enantiomeric excess, and impurity profile. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.