Description

Ethanol, 2-[2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Ethoxy]-, 1-(4-Methylbenzenesulfonate) is a high-purity, specialized chemical intermediate featuring a protected hydroxyl group, making it a critical building block for advanced organic synthesis. This compound is valued for its role in facilitating controlled, multi-step reactions where selective deprotection is required. It is primarily sought by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and other complex drug molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific functional group manipulation.
• Polymer Chemistry: Serves as a monomer or chain transfer agent in the development of specialized polymers with tailored properties.
• Protecting Group Chemistry: The tetrahydropyranyl (THP) group is utilized to protect alcohol functionalities during complex multi-step synthetic sequences.
• Linker Molecule: Employed in bioconjugation and the synthesis of prodrugs where a cleavable spacer is needed.
• Material Science Research: Used in the development of novel organic electronic materials and liquid crystals.

Basic Information

Product Name	Ethanol, 2-[2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Ethoxy]-, 1-(4-Methylbenzenesulfonate)
CAS No.	69502-32-5
Molecular Formula	C₁₆H₂₄O₇S
Molecular Weight	360.42 g/mol
Synonyms	2-[2-[(Tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethyl 4-methylbenzenesulfonate; 2-(2-(Tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl Tosylate; THP-protected PEG-tosylate; Ethanol, 2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]-, 1-(p-toluenesulfonate); PEG2-THP Tosylate; 2-(2-(Tetrahydro-2H-pyran-2-yloxy)ethoxy)ethanol p-toluenesulfonate; Tos-PEG2-THP; 4-Methylbenzenesulfonic acid 2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethanol, 2-[2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Ethoxy]-, 1-(4-Methylbenzenesulfonate) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.