Description

1-Chloro-3-(Ethoxy)Acetone is a versatile chlorinated ketone derivative with an ethoxy functional group, making it a valuable bifunctional building block in organic synthesis. This compound matters for its ability to introduce both reactive carbonyl and halogenated sites into target molecules, facilitating complex chemical transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring halogenated ketone or ether linkages.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where its reactive sites allow for structural diversification.
• Chemical Research & Development: Serves as a versatile electrophile and building block for novel heterocyclic compounds and fine chemicals.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to form carbon-carbon bonds.
• Polymer Chemistry: Potential monomer or modifier for specialty polymers, contributing specific functional groups to polymer chains.
• Flavor & Fragrance Industry: Intermediate for the synthesis of certain aroma chemicals and flavoring agents.

Basic Information

Product Name	1-Chloro-3-(Ethoxy)Acetone
CAS No.	69378-63-8
Molecular Formula	C5H9ClO2
Molecular Weight	136.58 g/mol
Synonyms	3-Ethoxy-1-chloroacetone; 1-Chloro-3-ethoxy-2-propanone; 3-Ethoxy-1-chloro-2-propanone; 1-Chloro-3-ethoxyacetone; Chloroethoxyacetone; Ethoxy Chloroacetone; α-Chloro-β-ethoxyacetone; 2-Propanone, 1-chloro-3-ethoxy-
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-(Ethoxy)Acetone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.10 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.