Description

2(3H)-Furanone, 3-Chlorodihydro-3-(Trifluoroacetyl)- (9Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a reactive lactone core with chlorinated and trifluoroacetyl functional groups, enabling precise chemical modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a building block for synthesizing specialized polymers or liquid crystals with unique electronic or optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cyclization reactions, ring-opening polymerizations, and as a precursor to other complex heterocycles.
• Fluorine Chemistry Research: An important compound for studying the effects of fluorine substitution on reactivity and physical properties in heterocyclic systems.

Basic Information

Product Name	2(3H)-Furanone, 3-Chlorodihydro-3-(Trifluoroacetyl)- (9Ci)
CAS No.	69243-05-6
Molecular Formula	C6H4ClF3O3
Molecular Weight	216.54 g/mol
Synonyms	3-Chloro-3-(trifluoroacetyl)dihydrofuran-2(3H)-one; 3-Chloro-3-(trifluoroacetyl)tetrahydrofuran-2-one; 3-Chlorodihydro-3-(trifluoroacetyl)-2(3H)-furanone; 3-Chloro-3-(2,2,2-trifluoroacetyl)oxolan-2-one; 69243-05-6; 3-(Trifluoroacetyl)-3-chlorodihydro-2(3H)-furanone
EINECS	Contact for details

Quality Control

Our 2(3H)-Furanone, 3-Chlorodihydro-3-(Trifluoroacetyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.