Description

2,4-Dichloro-3-Methylbenzenesulfonyl Chloride (Saltdata: Free) is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the sulfonamide functional group, a key moiety in the development of active pharmaceutical ingredients and specialty agrochemicals. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecules with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs), including diuretics, antibacterial agents, and protease inhibitors.
• Agrochemical Synthesis: Used in the manufacture of modern herbicides, fungicides, and plant growth regulators, where the sulfonamide group contributes to efficacy and selectivity.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing sulfonated dyes and pigments, enhancing solubility and color fastness.
• Polymer Modification: Employed to introduce sulfonyl chloride groups into polymer chains for subsequent functionalization, creating materials with specific ionic or surface properties.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial labs for exploring new synthetic pathways and creating novel chemical entities.
• Ligand Synthesis for Catalysis: Used to prepare specialized sulfonamide ligands for transition metal catalysis, improving reaction yields and selectivity.

Basic Information

Item	Details
Product Name	2,4-Dichloro-3-Methylbenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	69145-58-0
Molecular Formula	C7H5Cl3O2S
Molecular Weight	259.54 g/mol
Synonyms	3-Methyl-2,4-dichlorobenzenesulfonyl chloride; 2,4-Dichloro-3-methylbenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-2,4-dichloro-3-methylbenzene; 2,4-Dichloro-3-methylbenzenesulfonchlorid; Benzenesulfonyl chloride, 2,4-dichloro-3-methyl-; 2,4-Dichloro-3-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-3-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical and agrochemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.